Asking myself if round blocks had any advantages over v-blocks, I came up with this table. It’s based what my books say about production grinding, the video, your comments, and Jason’s drawing – the maths are too hard for me!

The performance of the two types are similar. The advantage of round blocks seems to be that they can be precisely made with a mill and lathe in an ordinary workshop, and could be bespoke to fit a particular milling table. The level of skill needed is moot – doesn’t seem that advanced to me, but much depends on the required precision.
Best to put figures on precision and accuracy, so we’re all on the same page. Using rough methods I often knock up parts that only need to be within 0.1mm, and though that keeps me happy, it’s not always acceptable! So instead of allowing speculation about what I mean by accuracy here, all dimensions and parallels must be ±0.005mm, a requirement that disqualifies rough blocks satisfactory for ordinary work-holding.
How easy are blocks to make? I have several DIY V-blocks, all approximately milled within near my usual ±0.02mm range. I can certainly stretch to ±0.01mm, and might get ±0.005mm at the cost of several rejects! Therefore, I suggest precision V-Blocks are significantly harder to make in a basic workshop than precision round blocks. Opposite is true in a factory where accurate V-Blocks are easily made by grinding. And in a factory many economies are possible, for example by using stock with a pre-rolled V, or roughing out with a big horizontal mill. Mass-production by grinding is quick and cheap and fundamentally more accurate than turning or milling. In contrast, round blocks require more operations, so I guess they’d be a shade more expensive to mass-produce, to no particular advantage.
So I buy off-the-shelf commercial v-blocks and mill bigger home-made V’s as necessary, ‘good enough’ rather than accurate. A caveat: though I work with pipe, it’s usually bendy plastic, not metal, so accuracy is limited by the material. So I won’t rush to make any round blocks – unless there’s a need, they’re a waste of time. But if I need to accurately mill a 4″ metal pipe, I shall remember they’re an option.
Of course my analysis could be wrong, or inappropriate to your needs. Perhaps I’ve missed something! Anyone decided to make a set of round blocks? If so, what for?
Dave