Graham It depends a lot on your setup and strategy is it CNC with ball-screws, if so I have a lot of experience with this stuff, Climb mill, stepover should be either 70% or 25% these angles give the cutter tooth the best entry angle, in addition it also gives the best exit angle as the tooth leaves the work the chip becomes unsupported and tends to bend and break off, this can damage the tooth, depth of cut I often go full width at 70% stepover and twice width at 25%, so for a 12mm HSS ripper machining a pocket in 6082 I would go with 12mm depth OC 8.4 SO circular ramp in at 3deg 3500 rpm 850mm fr, profiling I would go 3mm SO 24 depth same speed and feed.
However as you know, none of this is cast in stone you have to know your machine and its capabilities, also is it about metal removal rate or finish either way I would finish with a normal endmill for best finish.
A lot of the above comes from advice via Sandvik, I have a paper from them I could forward to you via email.
HTH
Shaun