Hi Rob,
My DW MK1 (all dims approx) has base approx 14.5" /37cm front to back and 20cm/8"wide. Cross slide / Y function, is 20cm/8" wide and moves 15cm/5.5" in and out from column.
X function/Table is 41cm/16.5" long. Travel, LH edges X to Y 10"/25.5cm. When table wound towards RH side to the extent of both LH edges level, the RH edges of X and Y are 21cm/8.25" apart. The table's RH edge to tip of handle is 20cm/10"
To sum up, from the RH side, extreme distance of handle tip is 40.5cm/16" from the RH edge of cross slide. You will of course need a bit more to accomodate your hand. On the LH side, space required will be min. 10"/25.5cm.
You will have to determine for yourself just how much "reasonable working clearance" amounts to.
Hope above makes sense and helpful. I think only certain items change for MK2 like table length and travel, but you may be able to check that on the lathes.co site.
Regards
John