I don’t think there is anything particularly difficult about the Wyvern. 3 points you might like to consider come to mind:
Wyvern was designed to made in cast iron but the Hemingway castings, apart from the fly wheels, are aluminium. The design for the exhaust valve seats directly in the casting which most builders seem to think isn’t a good idea in aluminium so use an insert similar to the inlet valve.
You might want to consider using an O ring rather than cast iron piston rings for better compression.
Cheap and readily available ball bearings can be used for the cam followers.
HTH,
Rod
Edit P.S. ETW’s design calls for 2:1 skew gears of the same diameter. These are not easy to come by and, I believe, Hemingway supply 45 degree gears of different diameters which don’t fit in with the design as drawn.