I don’t think it’ll be air, and isolation won’t help – I get the same noise from my towel rail when the system starts up as the pump initially runs at full speed then slows down, at which point the noise disappears (it’s intentionally set up like that).
It’s due to a lot of water tryng to get through a small (and not very flow-friendly) opening either at the lockshield valve or (more unlikely) the adjustable/thermostatic valve on one or more of the rads. Balancing and reducing pump speed should sort it out.
Given time, the water flow will erode the sharp edges inside the valves and reduce the problem, but that’s not really a practical solution. 🙂
Edit – you did deburr all the internal ends of the pipes when fitting as sharp edges there could cause the same sound?
Rob