I do similar all the time, as XD said rough it out with a two flute maybe 10mm dia cutter – 12mm pushing it a bit much with that machine though would take 19.4mm cutters, used to have one.
Use uncoated cutters and continually blow out the debris. Plus point very little coolant will be needed and will be contained within. Careful if using ER collet cutter may drop unknowingly or cut a taper, used to cop us out at work. General rule for aluminiums is you cannot have too much speed, people use 30000 rpm routers! As mentioned before get a feel for whats happening, you will know if the cutters doing its job, don't force it.
Once roughed near to size slap in a 4 flute long 6mm, check cutter flutes are at least 20mm. Downside is the cutter will flex so minor cuts to finish off to size climb milling (working anti clockwise) with bed locks nipped up will leave a good finish. Alternatively can use a long fluted 6mm with say flutes 10mm, shank will rub below that so keep plenty of coolant on.
Holding in a 4" vice will be more than adequate. Gripping force initially over the length to start with and will end up gripping on each ends 2.5mm = fine. Granted if using a 3" vice, around 5mm wall using 6082 aluminium it will start to collapse. If it moves then you tighten job back up, it will cut a taper.
Depth of cut passes you will have to suck it and see, key is get a feel for whats happening. ie if its tough going ease depth of cut off. You will hear the cutting change note when it starts to pick up and bind to the tool, this can be straight away or after several passes going down in depth. Aluminiums can be a right swine for binding up especially threads.