I would tend to agree with Speedy Builder, but it rather depends on where and how the z-axis lead screw is mounted and driven. From the photo provided, I assume that it drives the lead screw directly or via a toothed belt drive at the tailstock end. But that’s pure supposition on my part. What is the difficulty that you are experiencing exactly? More information, with more photos will help clarify the situation and hopefully lead to a solution.
I only have the single-axis version on my mini lathe and I find it easy to set up and any problems that I’ve had have been quickly addressed through an email exchange with the vendor.
John