For today just decided to drill and tap holes, whilst I wait for reamer and dowels. But will test all options suggested.
Picture below shows plate after spot drilling all (well most of) the holes and then drilling a 3mm through hole. The fixture plate is sat on a 3mm plywood base to prevent damage to the table. I did not want to raise it any further as the tenons on the bottom of the plate are locating it in the central slot on the table.

I said I had drilled most of the holes. No matter which way I moved the table in the Y axis and moved the head forward and backwards there was no way I could see to drill the final row of holes. Rather than disturb the current setup I will complete all the tapped holes and all bar the last row of 8 reamed holes prior to moving the milling head to to an extended position to get to the last row. Will have to use the edge finder on the outside edge and then move in the required 15mm or possibly it would be more accurate to fit some dowels in the last but one row and take a measurement from there.
All the holes to be tapped have been drilled 8.5mm and have just tapped 18 of them by hand after tea. The next 18 can wait till the morning, need to give my back a rest.
Colin