Am NOT a loco man, but realise that the wheels on each side of a steam loco must remain in the same relationship to each other to ensure freedom of movement. (In an extreme case, a two cylinder loco would not be self starting).
With regard to the strength of anaerobic sealants, they can be extremely strong. For many tears cars have been manufactured where the crown wheel is secured to the differential by such "adhesives", happily transmitting upwards of 100 bhp to the wheels.
In my own experience, I bought two ER chucks (ER25 and ER32) for use on the lathe, but had to fabricate backplates. Having smeared very old anaerobic retainer over both faces, the ER taper was clocked and tapped until running true within 0.0005", before tightening the retaining bolts. Some years later, I obtained and machined some Backplate castings to suit the ER Collet Chucks. Having slacked the bolts on the original set ups, it was impossible to remove the ER chuck from the fabricated backplate. (Stopped when I began to fear damaging the chuck with the strength of the blows from a copper/hide mallet) WAY past its "safe to use " date, but the retainer was extremely tough. So does anyone want a couple of 2.25 x 8 tpi threaded cast iron backplates?
Howard