Couple of thoughts –
Don't go anywhere near it with silicon(e), it won't stick to hardly nuffink (it's a gap filler) and once you've contaminated it with those little Si molecules nothing but nothing will stick to it., It's a common fallacy that it will seal a pressure joint, but it won't.
Some pipe fittings are injection moulded with ABS. At this time of night I'm struggling to remember if it's PVC glue that won't stick ABS, or the other way round, but I know one glue sticks (solvent welds) both and the other only sticks the one. But this assumes the valve is moulded from such. If you could put up a picture of the valve it might tell us what we're trying to deal with. If the ABS/PVC choice looks like the right line of logic I'll do the research.
Finally, anything Loctite related wrecks PVC or ABS, don't understand the chemistry but it won't seal no way no how, not never.
HTH Simon