Hallo Tony,
Yes, of course accurate positioning is possible on a mill without DROs. I often see reference to them here and I am sure they do make life much easier when fitted and that's certainly the impression I get. But I try to comment within the context of what I know and do myself, in the hope that this will be useful to others who might have similar constraints to mine (in either their skill levels or available machinery).
For many years, my workshop was 'lathe only', so my work – mostly small models and any required tooling, jigs (plus the odd washing machine part) had to be achieved within those constraints. I now effectively have three milling machines – a large horizontal (Victoria), a benchtop horizontal (Atlas MF) and a Taig (lathe mounted) vertical head, with both horizontals having vertical milling heads fitted. However, none of these machines are mill/drills – in the sense that they do not have drilling 'quills' with all vertical movement being via the knee, so drilling with them is just about doable but not exactly ideal.
Also, there is considerable wear and backlash in the two larger machines (that hopefully I will fix one day) but that I currently just "live with". My larger machines are also in the "cold" workshop that I don't get into too much in the winter, so again my small 'inside' lathe gets used for a lot of things than it might otherwise not do. So that is my "context" if you wish – the background against which I try to help some here…
So sure, I could use a mill (and it's dials) to do this work but I guess that if the work will fit in the four jaw or on the faceplate (and most of my work will do so) then that's what I tend to prefer to do, partly because I'm used to doing it way and partly because my mills are not ideal for this (though they are very useful for other things of course!). People with newer (vertical) mills, that generally have drilling quills, will quite likely have their own preferences and of course a CNC 'miller' will just pop in the co-ordinates and drill away. Good luck to them, they are very fortunate to have these facilities but I don't I'm afraid and probably never will have now.
So to be clear – I wasn't trying to have a dig at anyone who is lucky enough to have a jig borer or DRO equipped mill – I was just suggesting that some folk here will need to find other ways to do some things and suggesting ways to do them.
Regards,
IanT